The association between brain-derived neurotrophic factor and central pulse pressure after an oral glucose tolerance test.

I-Te Lee,Chen-Huan Chen,Jun-Sing Wang,Chia-Po Fu,Wen-Jane Lee,Kae-Woei Liang,Shih-Yi Lin,Wayne Huey-Herng Sheu

Clinica Chimica Acta（2018）

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摘要

•Central arterial stiffness with a wide pulse pressure predicts cardiovascular disease.•Arterial stiffening impairs postprandial vasodilatation.•Brain-derived neurotrophic factor (BDNF) can modulate vascular function.•A lower serum BDNF predicts a higher central pulse pressure after glucose intake.

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ACE,ARB,BDNF,BMI,BP,HOMA-IR,OGTT,PC

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