The paracrine effect of cobalt chloride on BMSCs during cognitive function rescue in the HIBD rat

Ying Dai,Wendi Li,Min Zhong,Jie Chen,Qian Cheng,Youxue Liu,Tingyu Li

Behavioural Brain Research（2017）

引用 9|浏览16

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摘要

•administration of CoCl2 activates HIF-1α and its target genes in BMSCs•administration of CoCl2 preconditioned BMSC culture medium with a micro-osmotic pump offers neuroprotection following hypoxia-ischemia damage•CoCl2 preconditioned BMSC culture medium treatment increased induction of LTP，which might be associated with GluR2

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关键词

AMPA,BMSCs,CoCl2,DMEM,DMOG,DMSO,EPO,fEPSP,HFS,HI,HIBD,HIF,IGF-1,LTP,PHD,2-ME2,VEGF

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