Regulation of gonadotropins by urocortin 2 in gonadotropic tumor LβT2 cells.

Neuroscience Letters(2017)

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摘要
•Ucn2 acts on gonadotrophs expressing the CRF2 receptor.•Ucn2 directly decreased the mRNA levels of both LH and FSH in the pituitary gonadotropic tumor cells.•A CRF2 receptor antagonist suppressed the Ucn2-induced decreases in LH and FSH mRNA levels.
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关键词
Corticotropin-releasing factor,Urocortin,Pituitary,Stress,Gonadotropin
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