Lipid production in Nannochloropsis gaditana is doubled by decreasing expression of a single transcriptional regulator

Imad Ajjawi,John Verruto, Moena Aqui,Leah B Soriaga,Jennifer Coppersmith, Kathleen Kwok, Luke Peach, Elizabeth Orchard,Ryan Kalb, Weidong Xu, Tom J Carlson,Kristie Francis, Katie Konigsfeld,Judit Bartalis, Andrew Schultz,William Lambert,Ariel S Schwartz, Robert Brown,Eric R Moellering

NATURE BIOTECHNOLOGY（2017）

引用 309|浏览11

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摘要

Lipid production in the oleaginous microalga Nannocholoropsis gaditana is doubled by decreasing the expression of a transcriptional regulator identified through a CRISPR–Cas9 reverse-genetics approach.

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关键词

Metabolic engineering,Metabolic engineering,Microbial genetics,Transcriptomics

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