Reconstruction of gene networks using prior knowledge

Mahsa Ghanbari
Mahsa Ghanbari

BMC Systems Biology, Volume 9, Issue 1, 2015, Pages 84-84.

Cited by: 8|Bibtex|Views13|Links
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Keywords:
Gene regulatory networks Network reconstruction Prior knowledge Bayesian networks

Abstract:

Reconstructing gene regulatory networks (GRNs) from expression data is a challenging task that has become essential to the understanding of complex regulatory mechanisms in cells. The major issues are the usually very high ratio of number of genes to sample size, and the noise in the available data. Integrating biological prior knowledge ...More

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