P4-085: memento: a national cohort on determinants and biomarkers of alzheimer's disease and associated disorders

sequence (n1⁄423), were evaluated on the Saykin scale modified for severity (Saykin-mod-sev), (Saykin, Reisberg modification, 2013), and an Emotional Severity Scale (ESS), (Guillo BenArous, 2013). We compared the scales with respect to scores on a battery of psychological tests and demographic variables, specifically, age, gender, and education. Results: We found a significant relationship between the Saykin ADNI Self Report Index and the Trail Making Test B (P1⁄40.009) (see figure). We also found a significant relationship between the Visual Analogue Scale and the Paired Associates Delayed Recall measure (p1⁄40.028). For the demographic variables a significant relationship was found with selected tests (see Figure). Conclusions: These findings could be of relevance for future prevention trials. Ultimately, we need to determine the sensitivity of temporally based scales in comparison with severity based scales and identify optimal predictors of eventual MCI and AD.