The effectiveness of reducing the amount of antibiotic resistant strains by promoting the antibiotic stewardship via antibiotic management team of a medical center

Methods: We evaluated the appropriateness of drug usage in hospitalized patients who received antimicrobial agents (second, third and fourth-line antibiotics) in a local community hospital during the period from January 2014 to September 2014. To enhance pharmacists’ participation in antimicrobial use evaluation, inappropriate selection of agents, dose, frequency, duration of antimicrobials or therapeutic drug-level monitoring was reported by pharmacists via telephone calls upon the delivery of computerized prescriptions.By the end of providing pharmacists’ suggestions, we use the Integrating Pharmacy Systems for an intpatient Physician Order Entry System to record suggestions. We used Excel and SPSS 18.0 for data analysis. Results: During the study period, a total of 2,534 records were assessed. The clinical pharmacists identified 100 drugrelated problems (DRPs) (3.9%). The most common DRPs related to frequency (35.8%), drug choice (22.8%), dosage (21.1%), therapeutic drug-level monitoring (11.4%) and others (8.9%). All doctor’s responses of acceptable rates was 83.0% of suggestions. Conclusions: Antimicrobial stewardship refers to coordinated interventions designed to improve and measure the appropriate use of antimicrobials by promoting the selection of the optimal antimicrobial drug regimen, dose, duration of therapy, and route of administration. The intervention program improved the appropriateness of antibacterial prescriptions.