Scaling probabilistic models of genetic variation to millions of humans
Nature Genetics(2016)
摘要
John Storey, David Blei and colleagues present a method, TeraStructure, for estimating population structure from human genomic data sets on a scale not possible with current methods. TeraStructure is able to analyze data from the Human Genome Diversity Panel and the 1000 Genomes Project in less than three hours.
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关键词
Population genetics,Computational biology and bioinformatics
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