Evaluation of chromosomal DNA damage, cytotoxicity, cytostasis, oxidative DNA damage and their relationship with endocrine hormones in patients with acute organophosphate poisoning.

•Organophosphates (OPs) poisoning is common in developing countries.•OPs were increased micronucleus (MN) and nucleoplasmic bridges (NPBs), apoptotic and necrotic cell frequencies.•These increases may be associated with some endocrine hormones in acute OPs poisoning.•MN and NPBs frequencies, apoptotic and necrotic cell frequencies decreased after treatment in acute OPs poisoning.