Effect of melatonin on sleep disorders in a monkey model of Parkinson's disease

H Belaid,Joelle Adrien,Carine Karachi,Etienne C Hirsch,Chantal Francois

Sleep Medicine（2015）

引用 25|浏览4

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摘要

•Dopaminergic neuronal death in parkinsonian macaques induced sleep disorders.•Melatonin with levodopa improved sleep disorders in parkinsonian macaques.•Melatonin treatment helps alleviate sleep disorders in people with Parkinson's disease.

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关键词

Melatonin,Parkinson's disease,Sleep disorders,MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine),Macaques,Monkeys

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