Pd-Catalyzed Heterocyclization During Sonogashira Coupling: Synthesis Of 3-Aryl-Substituted Imidazo[2,1-B]Thiazoles

Mohammad Bakherad,Ali Keivanloo,Hossein Nasrisfahani,Mersad Raeissi

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS（2011）

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摘要

The reaction of 4,5-diphenyl-2-propargylmercaptoimidazole with various aryl iodides catalyzed by Pd-Cu in the presence of triethylamine as base in dimethyl formamide (DMF) leads to the formation of 3-aryl-substituted imidazo[2,1-b]thiazoles.

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关键词

Aryl iodide, imidazothiazole, Pd catalyst, Sonogashira reaction

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