Micronization, characterization and in-vitro dissolution of shellac from PGSS supercritical CO2 technique.

Philip W Labuschagne,Brendon Naicker,Lonji Kalombo

International Journal of Pharmaceutics（2016）

引用 11|浏览3

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摘要

•Shellac can be foamed and micronized in supercritical CO2.•Supercritical CO2 accelerates molecular reactions is shellac.•Physico-chemical properties of shellac can be modulated by CO2 pressure and temperature.•Shellac dissolution behaviour can be modulated by CO2 pressure and temperature.

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关键词

Shellac,Supercritical carbon dioxide,Processing,In-situ foaming,Micronization,Dissolution

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