Propofol promotes cell apoptosis via inhibiting HOTAIR mediated mTOR pathway in cervical cancer.

Dan Zhang,Xin-hui Zhou,Jian Zhang,Yun-xiao Zhou,Jun Ying,Guo-qing Wu,Jian-hua Qian

Biochemical and Biophysical Research Communications（2015）

引用 81|浏览4

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摘要

•Propofol inhibited cell growth and increased cell apoptosis in cervical cancer.•Propofol reduced tumor size of cervical cancer in vivo.•HOTAIR overexpression promotes cervical carcinoma cell growth via mTOR regulation.•HOTAIR was involved in the effects of propofol on cervical cancer cell growth.

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关键词

Propofol,Cervical cancer,lncRNAs,mTOR

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