Cell proliferation and cell death are disturbed during prenatal and postnatal brain development after uranium exposure.

M F Legrand, Caroline Elie,Johanna Stefani, Natasha M Flores,C Culeux,Olivia Delissen, Carlos F Ibanez,Philippe Lestaevel, Peter S Eriksson,C Dinocourt

NeuroToxicology(2016)

引用 19|浏览8
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摘要
•DU did not accumulate until GD18 in the fetuses.•DU detected in pups could directly cause observed effects.•DU exposure during gestation and lactation caused alterations in neurogenesis.•Modifications of neurogenesis do not lead to major morphological changes in brain.
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关键词
Neurogenesis,Heavy metal,Brain development,Telencephalon,Dentate gyrus
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