Zolpidem withdrawal status dystonicus in the patient with advanced Parkinson's disease.

Zolpidem, a commonly prescribed medication to treat insomnia [ [1] Toner L.C. Tsambiras B.M. Catalano G. Catalano M.C. Cooper D.S. Central nervous system side effects associated with zolpidem treatment. Clin Neuropharmacol. 2000; 23: 54-58 Crossref PubMed Scopus (85) Google Scholar ], has been reported to improve symptoms in movement disorders, particularly primary and secondary dystonia, and Parkinson's disease (PD) [ 2 Miyazaki Y. Sako W. Asanuma K. Izumi Y. Miki T. Kaji R. Efficacy of zolpidem for dystonia: a study among different subtypes. Front Neurol. 2012; 3: 58 PubMed Google Scholar , 3 Ruzicka E. Roth J. Jech R. Busek P. Subhypnotic doses of zolpidem oppose dopaminergic-induced dyskinesia in Parkinson's disease. Mov Disord Off J Mov Disord Soc. 2000; 15: 734-735 Crossref PubMed Scopus (32) Google Scholar ]. We report a patient with idiopathic PD and associated (secondary) dystonia who developed dystonic status after abrupt zolpidem withdrawal.