Safety evaluation of phytase 50104 enzyme preparation (also known as VR003), expressed in Pseudomonas fluorescens, intended for increasing digestibility of phytate in monogastrics

•Phytase 50104 enzyme was tested in acute and subchronic studies.•Phytase 50104 enzyme was tested for its potential to induce genotoxicity.•There is no evidence of in vitro or in vivo genotoxicity or toxicity.•Phytase 50104 enzyme is safe for use in poultry and swine feed.