Glial precursors clear sensory neuron corpses during development via Jedi-1, an engulfment receptor

NATURE NEUROSCIENCE(2009)

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摘要
During development of the peripheral ganglia, 50% of neurons die by apoptosis. This study finds that satellite glial cell precursors clear these neuronal corpses in developing dorsal root ganglia and identifies some of the molecular components involved in this phagocytosis.
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关键词
neuroscience,phagocytosis,psychophysics,stem cells,electron microscope,molecular mechanics,computation,cortex,brainstem,functional imaging,behavior,physiology,cognitive science,membrane proteins,nervous system,molecular biology,nature,systems neuroscience,memory,apoptosis
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