Associations of Poly (ADP-Ribose) Polymerase1 abundance in calf skeletal muscle with walking performance in peripheral artery disease

Experimental Gerontology(2020)

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摘要
•PARP1 abundance in calf muscle does not differ between PAD and non-PAD.•Greater PARP1 abundance in calf muscle associated with poorer PAD six-minute walk.•Calf muscle marker of oxidative stress associated with poorer walking ability in PAD.
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关键词
Walking performance,Six-minute walk,Oxidative stress,Calf muscle,Peripheral artery disease (PAD),Ankle-brachial index (ABI)
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