Identification of 4-methyl-1,2,3,4,10,10a-hexahydropyrazino[1,2-a]indoles as 5-HT2C receptor agonists.

Bioorganic & Medicinal Chemistry Letters（2005）

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摘要

New 4-methyl-1,2,3,4,10,10a-hexahydropyrazino[1,2-a]indoles are 5-HT2C receptor agonists. Appropriately substituted, several analogs show high potency and appreciable selectivity against the other 5-HT2 receptor subtypes.

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关键词

5-HT2C receptor agonist,Pyrazino[1,2-a]indole

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