Synthesis and structure–activity relationships of N3-pyridylpyrazinones as corticotropin-releasing factor-1 (CRF1) receptor antagonists

Bioorganic & Medicinal Chemistry Letters（2010）

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摘要

The structure–activity relationships of a series of N3-pyridylpyrazinones as corticotropin-releasing factor-1 receptor antagonists was investigated.

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关键词

Corticotropin-releasing factor,CRF,Pyrazinone,G-protein coupled receptors,Pyridyl,Pyrimidyl

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