Absorption of β-methyl-digoxin determined after a single dose and under steady state conditions

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Keywords:
absorptionb-methyl-digoxinserum concentrationman

Abstract:

Single doses of ß-methyl-digoxin 0.4 mg were given to groups of 17 – 18 healthy volunteers as an intravenous infusion lasting 2 hours, or orally as Lanitop Liquidum® or Lanitop® tablets. The serum glycoside concentration and urinary glycoside excretion were measured over 8 and 32 h. The absolute bioavailability from the oral preparations ...More

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