Pharmacokinetics of metildigoxin and digoxin in geriatric patients with normal and elevated serum creatinine levels

Clinical pharmacokinetics, Volume 6, Issue 6, 1981, Pages 463-468.

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Abstract:

The pharmacokinetics of digoxin and metildigoxin were investigated in geriatric patients on maintenance treatment. Minimum serum glycoside concentrations were determined on 3 consecutive days, and the elimination rate over a withdrawal period of 4 to 6 days was studied. In patients with serum creatinine levels of less than or equal to 1.3...More

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