Development of Community Annotation Databases for Linking Genomes to Cellular Functions

Abstract: IntroductionThe roles of biological databases are changing in two important aspects. First, the data contentabout molecular structures and molecular functions is certainly not su#cient for the emerging fieldof systems biology or the Genomes to Life initiatives. It is necessary to somehow capture higher-levelstructures and functions, such as molecular interaction networks and cellular processes, and createnew databases that integrate both molecular and higher-level information. Secondly,...