Section on PET Radiopharmaceutical Sciences
National Institute of Mental Health, National Institutes of Health
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Dr. Pike’s Section is focused on developing novel radioactive probes (radiotracers) for the investigation of neuropsychiatric disorders with PET. This research mainly encompasses medicinal chemistry for probe discovery and radiochemistry for labeling candidate probes with a short–lived positron-emitter, invariably cyclotron-produced carbon-11 (t1/2 = 20 min) or fluorine-18 (t1/2 = 110 min).