Steven D. Leach - Gastrointestinal Surgical Research Group, Department of Surgery Yale University School of Medicine and West Haven Veterans Administration, New Haven, Connecticut 06510 USA

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A pancreatic cancer organoid platform identifies an inhibitor specific to mutant KRAS

Xiaohua Duan,Tuo Zhang,Lingling Feng,Neranjan de Silva, Benjamin Greenspun, Xing Wang,Jenna Moyer,M. Laura Martin,Rohit Chandwani,Olivier Elemento,Steven D. Leach,Todd Evans,

CELL STEM CELL（2024）

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Altered RNA splicing causes pancreatic cancer and exposes a therapeutic vulnerability

Natasha Pinto Medici, Diana Martinez Saucedo, Danny Lee, Li-Ting Ku,Robert Tseng, Xinning Shan, Tianyi Chu, Pablo Perez-Pinera,Vincent Cannataro,Jeffrey Townsend,Christine Iacobuzio-Donahue, Marie Robert,

CANCER RESEARCH（2024）

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Single-cell profiling of neoplastic cell populations in a KRAS-initiated zebrafish pancreatic cancer model

Somer M. Matar, Britton C. Goodale, Xiaoying Liu, Annie Katanga, Nicole F. Gallien, Sandra Blazquez,Direna Alonso-Curbelo,Steven D. Leach

CANCER RESEARCHno. 2 (2024)

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A common set of structurally distinct endogenous retroviruses predict survival in multiple human tumor types

Alexandra L. Massa, Himanshu Chintalapudi, Evelyn C. Coppenbarger,Jake M. Peterson,Walter N. Moss,H. Robert Frost,Steven D. Leach

biorxiv（2024）

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Data from Targeting eIF4A-Dependent Translation of KRAS Signaling Molecules

Kamini Singh,Jianan Lin,Nicolas Lecomte,Prathibha Mohan,Askan Gokce,Viraj R. Sanghvi,Man Jiang,Olivera Grbovic-Huezo,Antonija Burčul,Stefan G. Stark,Paul B. Romesser,Qing Chang,

crossref（2023）

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Figures S1-S8 from p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia

Audrey M. Hendley,Yue J. Wang,Kishore Polireddy, Janivette Alsina,Ishrat Ahmed,Kelly J. Lafaro, Hao Zhang,Nilotpal Roy, Samuel G. Savidge,Yanna Cao,Matthias Hebrok,Anirban Maitra,

crossref（2023）

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Supplementary figure S4 from Targeting eIF4A-Dependent Translation of KRAS Signaling Molecules

Kamini Singh,Jianan Lin,Nicolas Lecomte,Prathibha Mohan,Askan Gokce,Viraj R. Sanghvi,Man Jiang,Olivera Grbovic-Huezo,Antonija Burčul,Stefan G. Stark,Paul B. Romesser,Qing Chang,

crossref（2023）

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Supplementary Figure S1 from Targeting eIF4A-Dependent Translation of KRAS Signaling Molecules

Kamini Singh,Jianan Lin,Nicolas Lecomte,Prathibha Mohan,Askan Gokce,Viraj R. Sanghvi,Man Jiang,Olivera Grbovic-Huezo,Antonija Burčul,Stefan G. Stark,Paul B. Romesser,Qing Chang,

crossref（2023）

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Data from <i>EIF1AX</i> and <i>RAS</i> Mutations Cooperate to Drive Thyroid Tumorigenesis through ATF4 and c-MYC

Gnana P. Krishnamoorthy,Natalie R. Davidson,Steven D. Leach,Zhen Zhao,Scott W. Lowe,Gina Lee,Iňigo Landa,James Nagarajah,Mahesh Saqcena,Kamini Singh,Hans-Guido Wendel,Snjezana Dogan,

crossref（2023）

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A targetable pathway to eliminate TRA-1-60⁺/TRA-1-81⁺ chemoresistant cancer cells

Lei Tan,Xiaohua Duan, Pratyusha Mutyala,Ting Zhou,Sadaf Amin,Tuo Zhang,Brian Herbst,Gokce Askan,Tomer Itkin,Zhaoying Xiang, Fabrizio Michelassi, Michael D. Lieberman,

JOURNAL OF MOLECULAR CELL BIOLOGYno. 6 (2023)

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