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个人简介
Research Interests:
Epilepsy
Alzheimer’s disease
drug development
preclinical research
translational research
neuroscience
pharmacology
Dr. Barker-Haliski’s research interests at the University of Washington support the development of novel animal models for the preclinical evaluation and characterization of investigational therapies for epilepsy in special patient populations, including pharmacoresistant epilepsy and epilepsy in the elderly. Her research seeks to understand the impact of aging and aging-related neurological disorders on seizure susceptibility, pharmacotherapeutic response, and long-term disease outcomes. She actively collaborates with UW faculty in the School of Medicine to develop novel preclinical platforms to identify novel therapeutic targets for antiseizure drug discovery for elderly patients with epilepsy. Further, she is interested in differentiating the available, well-established animal models from next-generation animal seizure and epilepsy models to best identify more effective therapies for the treatment and prevention of epilepsy in patients with drug-resistant epilepsy.
Epilepsy
Alzheimer’s disease
drug development
preclinical research
translational research
neuroscience
pharmacology
Dr. Barker-Haliski’s research interests at the University of Washington support the development of novel animal models for the preclinical evaluation and characterization of investigational therapies for epilepsy in special patient populations, including pharmacoresistant epilepsy and epilepsy in the elderly. Her research seeks to understand the impact of aging and aging-related neurological disorders on seizure susceptibility, pharmacotherapeutic response, and long-term disease outcomes. She actively collaborates with UW faculty in the School of Medicine to develop novel preclinical platforms to identify novel therapeutic targets for antiseizure drug discovery for elderly patients with epilepsy. Further, she is interested in differentiating the available, well-established animal models from next-generation animal seizure and epilepsy models to best identify more effective therapies for the treatment and prevention of epilepsy in patients with drug-resistant epilepsy.
研究兴趣
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EPILEPSIA (2024)
Inga Erickson,Dannielle K. Zierath,Stephanie Davidson, Seongheon Rho, Kristen Peagler, Kenneth E. Thummel,Aaron Ericsson,Melissa Barker-Haliski
ASPET 2024 Annual Meeting Abstract - Translational Systems and Clinical Pharmacology (2024)
Progress in Neurobiology (2024): 102591-102591
International journal of molecular sciencesno. 5 (2023): 4848-4848
IBRO Neuroscience Reports (2023): S390-S391
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