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Early on, Dr. Salisbury was fortunate to do pioneering studies that led to discovery of the protein centrin, which at the time was one of only a handful of centrosome proteins to be identified. Dr. Salisbury and his colleagues were the first to clone two of the human centrin genes and establish the crystal structure for this protein. Dr. Salisbury's group established centrin as an important calcium-sensitive regulator of centrosome behavior.
Using comparative proteomics, reverse genetics, and molecular and cell biology techniques, Dr. Salisbury's group helped to define the cell biology and molecular mechanisms that control centrosome dynamics and centriole duplication. His research program has a longstanding emphasis on regulation of centrosome dynamics during the cell cycle, as well as centrosome amplification and genomic instability in breast cancer.
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论文共 198 篇作者统计合作学者相似作者
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CELLSno. 10 (2023): 1356-1356
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Ramanakumar Sankar,Kameswara Bharadwaj Mantha,Lucy Fortson,Helen Spiers,Thomas Pengo, Douglas Mashek, Myat Mo, Mark Sanders, Trace Christensen,Jeffrey Salisbury,Laura Trouille
CoRR (2023)
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Kidney360no. 10 (2022): 1672-1682
Jennifer Ayers-Ringler,Jennifer S McDonald, Margaret A Connors,Cody R Fisher, Susie Han,Daniel R Jakaitis, Bradley Scherer, Gabriel Tutor,Katheryn M Wininger,Daying Dai,Doo-Sup Choi,Jeffrey L Salisbury,
arxiv(2022)
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bioRxiv (Cold Spring Harbor Laboratory) (2021)
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