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Our laboratory investigates the roles of virus-host interactions in replication and pathogenesis. We study RNA viruses, including hepatitis C virus, dengue virus, Zika virus, and noroviruses. These are medically important viruses, causing cirrhosis/liver cancer, hemorrhagic fever, birth defects, and severe GI disease, respectively. We have identified ~100 host cofactors of viral replication. We now study the importance of these cellular genes in diverse steps of the viral life cycle, including entry, the regulation of viral protein translation and RNA replication, modulation of cellular lipid metabolism, the establishment of viral replication complexes, the secretion of infectious virus, and control of infection by the innate immune system.
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论文共 101 篇作者统计合作学者相似作者
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Cosimo Cianfarini, Luise Hassler,Jan Wysocki, Abdelsabour Hassan,Vlad Nicolaescu,Derek Elli,Haley Gula,Amany M. Ibrahim,Glenn Randall,Jack Henkin,Daniel Batlle
Hannah Faisal Almubarak,Wuwei Tan,Andrew D Hoffmann,Juncheng Wei,Lamiaa El-Shennawy, Joshua R Squires,Yuanfei Sun,Nurmaa K Dashzeveg, Brooke Simonton,Yuzhi Jia,Radhika Iyer,Yanan Xu,
bioRxiv : the preprint server for biology (2024)
PLoS pathogensno. 12 (2023): e1011887-e1011887
Life science allianceno. 7 (2023): e202301969-e202301969
Mariya Syed, Cosimo L. Cianfarini, Luise Hassler,Minghao Ye,Jan Wysocki, Yashpal S. Kanwar,Dominique Missiakas,Glenn Randall,Daniel Batlle
Journal of the American Society of Nephrologyno. 11S (2022): 331-331
Luise Hassler,Jan A. Wysocki,Ian Gelarden,Nigar Khurram,Vlad Nicolaescu,Anastasia Tomatsidou,Haley Gula,Glenn Randall, Dominique Missiakas, Jack Henkin, Daniel C. Battle
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