Charles L. Sawyers

基本信息

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职业迁徙

个人简介

Clinical Expertise
Leukemias; New Drug Development

He has identified cell signaling components critical to the growth of cancer cells in chronic myeloid leukemia, prostate and other cancers, resulting in the development of multiple FDA-approved inhibitors in clinical use today.

研究兴趣

论文共 499 篇作者统计合作学者相似作者

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Single Cell Analysis of Treatment-Resistant Prostate Cancer: Implications of Cell State Changes for Cell Surface Antigen Targeted Therapies

Samir Zaidi, Jooyoung Park,Joseph M Chan,Martine P Roudier,Jimmy L Zhao,Anuradha Gopalan,Kristine M Wadosky,Radhika A Patel,Erolcan Sayar,Wouter R Karthaus, D Henry Kates,Ojasvi Chaudhary,

bioRxiv : the preprint server for biology (2024)

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Role of tumor microenvironment derived nrg1 in androgen resistance: implications for a novel prostate cancer treatment strategy

Brian Shinder,Ninghui Mao, Nazifa Salsabeel,Zeda Zhang,Charles L. Sawyers,Brett S. Carver

Urologic Oncology: Seminars and Original Investigations (2024)

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ERG activates a stem-like proliferation-differentiation program in prostate epithelial cells with mixed basal-luminal identity

Weiran Feng,Erik Ladewig, Nazifa Salsabeel,Huiyong Zhao,Young Sun Lee,Anuradha Gopalan, Matthew Lange,Hanzhi Luo,Wenfei Kang,Ning Fan, Eric Rosiek,Elisa de Stanchina,

biorxiv（2024）

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Timing of treatment shapes the path to androgen receptor signaling inhibitor resistance in prostate cancer

Eugine Lee, Zeda Zhang, Chi-Chao Chen, Danielle Choi, Aura C Agudelo Rivera, Eliot Linton, Yu-Jui Ho, Jillian Love, Justin LaClair, John Wongvipat,Charles L Sawyers

bioRxiv : the preprint server for biology (2024)

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Strategies to decrease inequalities in cancer therapeutics, care and prevention: Proceedings on a conference organized by the Pontifical Academy of Sciences and the European Academy of Cancer Sciences, Vatican City, February 23-24, 2023

Ulrik Ringborg,Joachim von Braun,Julio Celis,Michael Baumann,Anton Berns,Alexander Eggermont, Edith Heard, Manuel Heitor,Mammen Chandy,Chien-Jen Chen,Alberto Costa,Francesco De Lorenzo,

Molecular oncologyno. 2 (2024): 245-279

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The neuroendocrine transition in prostate cancer is dynamic and dependent on ASCL1

Rodrigo Romero,Tinyi Chu, Tania J. Gonzalez-Robles, Perianne Smith,Yubin Xie, Harmanpreet Kaur, Sara Yoder,Huiyong Zhao, Chenyi Mao,Wenfei Kang, Maria Pulina, Kayla E. Lawrence,

biorxiv（2024）

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Strategies to decrease inequalities in cancer therapeutics, care and preventionProceedings on a conference organized by the Pontifical Academy of Sciences and the European Academy of Cancer Sciences, Vatican City, February 23-24, 2023