基本信息
浏览量:0
职业迁徙
个人简介
Research
Multiple Sclerosis
Multiple sclerosis is one of the most prevalent diseases of the central nervous system, affecting over two million people worldwide. Canada has one of the highest rates of MS in the world with an estimated 75,000 Canadians living with this disease. The economical and personal burden of this disease makes unraveling its causes and the development of knowledge based treatments a high priority.
Familial Genetics
Approximately 10-15% of all patients suffering from multiple sclerosis have a first or second degree relative also diagnosed with the disease. The aggregation of multiple sclerosis within families highlights the existence of a single major genetic component determining the onset of disease in these patients.
Population Analysis
Over 13,000 biological samples from patients and healthy controls have been collected for the identification of genetic risk factors of multiple sclerosis. In contrast to the rare variants of strong effect observed in familial forms, risk variants are common genetic changes that results in a moderate increase to develop disease.
Multiple Sclerosis
Multiple sclerosis is one of the most prevalent diseases of the central nervous system, affecting over two million people worldwide. Canada has one of the highest rates of MS in the world with an estimated 75,000 Canadians living with this disease. The economical and personal burden of this disease makes unraveling its causes and the development of knowledge based treatments a high priority.
Familial Genetics
Approximately 10-15% of all patients suffering from multiple sclerosis have a first or second degree relative also diagnosed with the disease. The aggregation of multiple sclerosis within families highlights the existence of a single major genetic component determining the onset of disease in these patients.
Population Analysis
Over 13,000 biological samples from patients and healthy controls have been collected for the identification of genetic risk factors of multiple sclerosis. In contrast to the rare variants of strong effect observed in familial forms, risk variants are common genetic changes that results in a moderate increase to develop disease.
研究兴趣
论文共 121 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
medRxiv : the preprint server for health sciences (2024)
Alison M Pagalilauan, Elif Everest, Suzanna Rachimi,Daniel Reich,Alex D Waldman,A Dessa Sadovnick,Carles Vilariño-Guell, Michael J Lenardo
medRxiv : the preprint server for health sciences (2024)
Roland Dominic G. Jamora,Andrew A. Hicks,Inke R. König,Sylvie Delcambre,Theresa Lüth,Susen Schaake,Kobi Wasner,Jenny Ghelfi,Max Borsche,Carles Vilariño‐Güell, F. Hentati, Elisabeth Luisa Germer,
Brainno. 7 (2022): 2753-2765
引用0浏览0引用
0
0
medRxiv (Cold Spring Harbor Laboratory) (2022)
Genesno. 12 (2022)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn