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Research Themes
Synthesis/Catalysis
Green and Sustainable Chemistry themes
Research Description
Our research interests lie in the development of new and efficient methods to synthesize organic molecules and new materials via transition metal catalysis. This is often directed towards compounds of biological importance or potential new drug cores. We are also exploring the application of metal catalysis to the synthesis of new classes of polymers. In developing these reactions, we rely upon mechanistic insights into transition metal based transformations, and their extension to new and practical synthetic methods.
Research in his group focuses on the discovery and mechanistic understanding of new approaches to chemical synthesis by transition metal catalysis. Their work has demonstrated that transition metal-based reactions can be used to design efficient, one step syntheses of a range of important core structures directly from available building blocks, as an alternative to classic multistep protocols. His group has also developed the general concept of using ion pairing with chiral anions as an alternative to chiral ligands in asymmetric transition metal catalysis. More recently, his lab has discovered new classes of 1,3-dipoles for use in cycloaddition reactions (phospha-Münchnones), as well as approaches to polymer synthesis based upon metal catalyzed multicomponent reactions, and developed mechanistic insights into each of these metal catalyzed processes.
Professor Arndtsen is the recipient of a DuPont Aid in Education Award (2000), and one of only a handful in Canada to be awarded an NSERC Accelerator Grant for Exceptional New Opportunities (2004). He was his department’s nominee for a Leo Yaffe Teaching award in 1998, and in 2005 was named a William Dawson Scholar at McGill University. In 2011 he was named a James McGill Professor of Chemistry, a Canadian Research Chair Tier I equivalent at McGill University.
Synthesis/Catalysis
Green and Sustainable Chemistry themes
Research Description
Our research interests lie in the development of new and efficient methods to synthesize organic molecules and new materials via transition metal catalysis. This is often directed towards compounds of biological importance or potential new drug cores. We are also exploring the application of metal catalysis to the synthesis of new classes of polymers. In developing these reactions, we rely upon mechanistic insights into transition metal based transformations, and their extension to new and practical synthetic methods.
Research in his group focuses on the discovery and mechanistic understanding of new approaches to chemical synthesis by transition metal catalysis. Their work has demonstrated that transition metal-based reactions can be used to design efficient, one step syntheses of a range of important core structures directly from available building blocks, as an alternative to classic multistep protocols. His group has also developed the general concept of using ion pairing with chiral anions as an alternative to chiral ligands in asymmetric transition metal catalysis. More recently, his lab has discovered new classes of 1,3-dipoles for use in cycloaddition reactions (phospha-Münchnones), as well as approaches to polymer synthesis based upon metal catalyzed multicomponent reactions, and developed mechanistic insights into each of these metal catalyzed processes.
Professor Arndtsen is the recipient of a DuPont Aid in Education Award (2000), and one of only a handful in Canada to be awarded an NSERC Accelerator Grant for Exceptional New Opportunities (2004). He was his department’s nominee for a Leo Yaffe Teaching award in 1998, and in 2005 was named a William Dawson Scholar at McGill University. In 2011 he was named a James McGill Professor of Chemistry, a Canadian Research Chair Tier I equivalent at McGill University.
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R. Garrison Kinney, José Zgheib, Pierre-Louis Lagueux-Tremblay, Cuihan Zhou,Haifeng Yang, Jingwei Li,Donald R. Gauthier Jr,Bruce A. Arndtsen
Nature Chemistrypp.1-8, (2024)
R. Garrison Kinney, José Zgheib, Pierre-Louis Lagueux-Tremblay, Cuihan Zhou,Haifeng Yang, Jingwei Li,Donald R. Gauthier Jr,Bruce A. Arndtsen
Research Square (Research Square)pp.1-8, (2024)
Chemical communications (Cambridge, England)no. 6 (2023): 728-731
Organometallicsno. 21 (2022): 2903-2908
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