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个人简介
My laboratory develops new treatments for neurodegenerative diseases such as Huntington’s disease. We do this by first developing transgenic mouse models of specific human diseases, and then by testing new disease treatments in these mouse models. The YAC128 mouse model of Huntington’s disease accurately replicates the changes seen in humans with this disease, and is a critical tool that permits my laboratory to evaluate new treatment strategies in mice prior to undertaking large-scale clinical trials in human patients. Currently, my work is primarily focused on transgenic mouse models of Huntington’s disease, but in the future will expand to utilize the same standardized approach to investigate new therapeutics in mouse models of other devastating neurodegenerative disorders, such as ALS, prion disease, Parkinson's, and Alzheimer's disease.
研究兴趣
论文共 322 篇作者统计合作学者相似作者
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Nicholas S. Caron,Amirah E. -E. Aly,Hailey Findlay Black,Dale D. O. Martin,Mandi E. Schmidt, Seunghyun Ko, Christine Anderson, Emily M. Harvey, Lorenzo L. Casal, Lisa M. Anderson, Seyed M. R. Rahavi,Gregor S. D. Reid,
JOURNAL OF CONTROLLED RELEASE (2024): 27-44
Annabelle Coleman,Mackenzie T Langan,Gaurav Verma, Harry Knights,Aaron Sturrock,Blair R Leavitt,Sarah J Tabrizi,Rachael I Scahill,Nicola Z Hobbs
Journal of Huntington's Diseasepp.1-11, (2024)
Ralf Reilmann,Karen E Anderson,Andrew Feigin,Sarah J Tabrizi,Blair R Leavitt,Julie C Stout,Paola Piccini,Robin Schubert,Pippa Loupe, Anna Wickenberg,Beth Borowsky, Gail Rynkowski,
Ralf Reilmann,Karen E. Anderson,Andrew Feigin,Sarah J. Tabrizi,Blair R. Leavitt,Julie C. Stout,Paola Piccini,Robin Schubert,Pippa Loupe, Anna Wickenberg,Beth Borowsky, Gail Rynkowski,
LANCET NEUROLOGYno. 3 (2024): 243-255
Ralf Reilmann,Karen E Anderson,Andrew Feigin,Sarah J Tabrizi,Blair R Leavitt,Julie C Stout,Paola Piccini,Robin Schubert,Pippa Loupe, Anna Wickenberg,Beth Borowsky, Gail Rynkowski,
The Lancet. Neurologyno. 3 (2024): 243-255
Nicholas S. Caron,Lauren M. Byrne,Fanny L. Lemarié, Jeffrey N. Bone,Amirah E.-E. Aly,Seunghyun Ko, Christine Anderson,Lorenzo Casal,Austin M. Hill, David J. Hawellek,Peter McColgan,Edward J. Wild,
crossref(2024)
OPHTHALMOLOGY AND THERAPYno. 4 (2023): 2049-2068
Fabricio Pio,Blair R. Leavitt
Contemporary clinical neurosciencepp.19-44, (2023)
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