基本信息
浏览量:0
职业迁徙
个人简介
Research Interests
The research in the Goldstein laboratory is focused on the intersection between cancer biology, stem cell biology and metabolism. During his graduate work, Dr. Goldstein described the isolation of epithelial progenitor cells from mouse and human prostate tissue and demonstrated the capacity of progenitor cells to initiate prostate cancer in response to oncogenic transformation. Following up on this work, Dr. Goldstein and colleagues determined that prostate cancer can evolve from a basal cell of origin to a luminal-like tumor-propagating cell population. More recently, the Goldstein laboratory has been investigating the interplay between inflammation, epithelial progenitor cells, and tumorigenesis, using a combination of mouse and human tissue models. The main goals of the lab are to elucidate the cellular and molecular mechanisms promoting epithelial cancer initiation, progression and resistance to treatment.
The research in the Goldstein laboratory is focused on the intersection between cancer biology, stem cell biology and metabolism. During his graduate work, Dr. Goldstein described the isolation of epithelial progenitor cells from mouse and human prostate tissue and demonstrated the capacity of progenitor cells to initiate prostate cancer in response to oncogenic transformation. Following up on this work, Dr. Goldstein and colleagues determined that prostate cancer can evolve from a basal cell of origin to a luminal-like tumor-propagating cell population. More recently, the Goldstein laboratory has been investigating the interplay between inflammation, epithelial progenitor cells, and tumorigenesis, using a combination of mouse and human tissue models. The main goals of the lab are to elucidate the cellular and molecular mechanisms promoting epithelial cancer initiation, progression and resistance to treatment.
研究兴趣
论文共 95 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Cheryl L Wang,Jessica M Skeie,Chantal Allamargot,Andrew S Goldstein,Darryl Y Nishimura, James M Huffman,Benjamin T Aldrich, Gregory A Schmidt,Leandro B C Teixeira,Markus H Kuehn, Mark Yorek,Mark A Greiner
The American journal of pathology (2024)
JOURNAL OF SEXUAL MEDICINE (2024)
Cancer researchno. 9 (2024): 1382-1383
Tara Symonds,Sheryl A Kingsberg,James A Simon,Robin Kroll,Stanley E Althof,Sharon J Parish, Katherine A Cornell, Isabella F Johnson,Andrew T Goldstein
SCIENCE SIGNALINGno. 810 (2023): eabo5213-eabo5213
Preston D. Crowell,Jenna M. Giafaglione,Anthony E. Jones, Nicholas M. Nunley,Takao Hashimoto,Amelie M.L. Delcourt,Anton Petcherski, Raag Agrawal,Matthew J. Bernard,Johnny A. Diaz,Kylie Y. Heering,Rong Rong Huang,
Cell Reportsno. 10 (2023): 113221-113221
Cancer Researchno. 11_Supplement (2023): B002-B002
引用0浏览0引用
0
0
Jenna M Giafaglione,Preston D Crowell, Amelie M L Delcourt,Takao Hashimoto,Sung Min Ha, Aishwarya Atmakuri, Nicholas M Nunley, Rachel M A Dang, Mao Tian, Johnny A Diaz, Elisavet Tika, Marie C Payne,
Nature cell biologyno. 12 (2023): 1821-1832
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn