Research Summary
    Following the successful completion of the Human Genome Project, the challenge now is to decipher the information encoded within the human genetic code — including genes, regulatory controls and cellular circuitry. Such understanding is fundamental to the study of physiology in both health and disease. At the Broad Institute, my lab collaborates with other to discover and understand the genes responsible for rare genetic diseases, common diseases, and cancer; the genetic variation and evolution of the human genome; the basis of gene regulation via enhancers, long non-coding RNAs, and three-dimensional folding of the genome; the developmental trajectories of cellular differentiation; and the history of the human population.
    James R. Killian, Jr. Faculty Achievement Award, MIT, 2016
    Block Memorial Award for Distinguished Achievement in Cancer Research, Ohio State University, 2013
    AAAS Philip Hauge Abelson Prize, 2015
    Breakthrough Prize in Life Sciences, 2013
    Harvey Prize for Human Health, Technion University, Israel, 2012
    Dan David Prize, 2012
    Albany Prize in Medicine and Biomedical Research, Albany Medical College, 2010
    Gairdner Foundation International Award, Canada, 2002
    Max Delbruck Medal, Berlin, 2001
    MacArthur Foundation, MacArthur Fellowship, 1987